PNC-27 peptide vial

Description

The PNC-27 peptide vial from Umbrella Labs comes as freeze-dried powder in a sealed vial. You can choose 2mg, 5mg or 10mg. Each batch is tested by LC-MS to 99% purity or higher. Prices start at $69.99. It’s sold for laboratory research only.

Browse the rest of our peptide vials for related compounds.

What is PNC-27?

PNC-27 is a 32-residue peptide that joins a sequence from p53 (residues 12-26, the HDM-2 binding region) to a membrane-penetrating sequence. It’s studied for its effects on cancer cell membranes.

It’s only been studied in cells and animals.

PNC-27 peptide vial specifications

• Compound: PNC-27
• CAS number: 1159861-00-3
• Molecular formula: C188H293N53O44S
• Molecular weight: 4031.7
• Purity: 99% or higher, tested by LC-MS
• Size: 2mg, 5mg and 10mg
• Form: Lyophilized (freeze-dried) powder in a sealed vial
• Storage: Keep it in the fridge at 2 to 8°C and don’t freeze it
• Use: laboratory research only, not for human or veterinary use

What studies say about PNC-27

Sarafraz-Yazdi and colleagues reported in PNAS (2010) that PNC-27 bound HDM-2 on cancer cell membranes and formed pores that killed the cells, while untransformed cells were spared.

Follow-up work looked at leukemia and pancreatic cancer cell lines.

Search PubMed for the full studies. We stick to what’s been published.

Reconstituting PNC-27 for research

PNC-27 arrives as a freeze-dried (lyophilized) powder in a sealed glass vial. It has to be dissolved before use, and for most peptides that means bacteriostatic water. Let the water run slowly down the inside wall of the vial, then swirl gently until the solution is clear. Don’t shake it.

The amount of water you add sets the concentration. For example, adding 2mL of bacteriostatic water to a 2mg vial gives 1mg per mL. Write the volume and the date on the label so anyone picking up the vial later knows what’s in it.

We sell bacteriostatic water in 30mL vials, and acetic acid solution for the few peptides that don’t dissolve well in water.

Choosing a PNC-27 vial size

The vial comes in 2mg, 5mg and 10mg. The contents are the same apart from the amount, so the choice comes down to how much your study needs and how quickly you’ll use a mixed vial.

Mixed peptides don’t last as long as dry ones, so several smaller vials can work out better than one large one if you’re running a slow study.

Purity testing for PNC-27

Every batch of PNC-27 is checked with liquid chromatography-mass spectrometry (LC-MS) before it goes on sale. LC-MS separates a sample into its parts and identifies each one by mass, so it confirms what the compound is and how much of the sample it makes up. The current batch tested at 99% or higher.

Small differences between batches are normal, so write the batch number from the label into your records. If something looks wrong when your order arrives, like discoloured powder or a cloudy solution, set it aside and don’t use it.

How to store PNC-27

Keep it in the fridge at 2 to 8°C and don’t freeze it. Once mixed, keep the vial in the fridge and use it within a few weeks. Unmixed vials keep much longer, so only reconstitute what you need. Label anything you decant with the compound, amount and date, and keep it out of reach of children and pets.

Common questions about the PNC-27 peptide vial

Does PNC-27 come with water to mix it?

No. The vial holds only the freeze-dried powder. Add bacteriostatic water to your order if you don’t already have some.

How long does mixed PNC-27 last?

Kept in the fridge, most reconstituted peptides are good for a few weeks. Unmixed vials last much longer, especially in the fridge or freezer.

Is the PNC-27 peptide vial in stock?

Yes. Every option on this page is in stock and ready to ship.

More research peptides like PNC-27

Other products in the same range include Prostamax peptide vial, Peptide T peptide vial, PT-141 peptide vial and PEG-MGF peptide vial. Our main Research Peptides page lists everything in the category.

Buy PNC-27 peptide vial from Umbrella Labs

Ordering takes a minute. Pick your option above, add it to your cart and check out. The PNC-27 peptide vial is in stock and ready to ship. Need other compounds for the same study? Browse peptide vials or our lab supplies.

Sold for laboratory research use only. It isn’t for human or veterinary use, and it isn’t a food, drug or cosmetic.