Description
The TAK-653 powder from Umbrella Labs comes as loose powder, sold by weight. Each batch is tested by LC-MS to 99% purity or higher. It’s $299.99. It’s sold for laboratory research only.
Prefer a different format? We also stock TAK-653 liquid and TAK-653 capsules. See all nootropic powders for more options in this format.
What is TAK-653?
TAK-653 is an AMPA receptor potentiator from Takeda with very low agonist activity. That profile is meant to give the benefits of AMPA signaling without seizure risk.
It’s in the same family as HBT1.
TAK-653 powder specifications
- Compound: TAK-653 (9E3Toe5riz)
- CAS number: 1358751-06-0
- Molecular formula: C19H23N3O3S
- Molecular weight: 373.47
- Purity: 99% or higher, tested by LC-MS
- Amount: 1g
- Form: Loose powder
- Storage: Keep it in a cool, dry place away from direct sunlight
- Use: laboratory research only, not for human or veterinary use
TAK-653 in published research
Takeda researchers reported antidepressant-like effects in rodents.
Takeda ran a phase 2 trial in treatment-resistant depression.
The original papers are on PubMed if you’d like to read them in full.
Weighing and handling TAK-653 powder
Loose powder is the most flexible way to buy TAK-653. You can weigh any amount you need, dissolve it in your own solvent, or fill your own capsules. It’s also the cheapest format per milligram.
For small amounts you’ll want a scale that reads to at least 0.01g, and ideally 0.001g. Our digital scale and micro scoops make it easier to get consistent measurements. Weigh onto clean weighing paper, and close the bag or jar straight after so the powder doesn’t pick up moisture.
Making a solution from TAK-653 powder
To make a stock solution, decide on the final volume and concentration first. For 30mL at 10mg/mL you’d weigh 300mg of TAK-653, dissolve it in about 25mL of solvent, then top up to exactly 30mL.
Check the compound’s solubility in your chosen solvent before you start, and try a small test amount first. Store the finished solution in a labelled glass bottle.
TAK-653 quality and testing
We test each batch of TAK-653 by LC-MS, which pairs liquid chromatography with mass spectrometry. The chromatography splits the sample into its components and the mass spectrometer identifies them, which tells you both identity and purity. This batch came in at 99% or higher.
Small differences between batches are normal, so write the batch number from the label into your records. If something looks wrong when your order arrives, like discoloured powder or a cloudy solution, set it aside and don’t use it.
How to store TAK-653
Keep it in a cool, dry place away from direct sunlight. Use a clean, dry scoop each time, and reseal the container straight away. Label anything you decant with the compound, amount and date, and keep it out of reach of children and pets.
Common questions about the TAK-653 powder
What can I dissolve TAK-653 powder in?
That depends on the compound’s solubility and your protocol. Check the solubility data for your solvent first, and test a small amount before making up a full batch.
What scale do I need?
One that reads to 0.01g at minimum, and 0.001g for very small amounts. Our pocket scale reads to 0.01g.
Is the TAK-653 powder in stock?
Yes. Every option on this page is in stock and ready to ship.
More nootropics like TAK-653
If you’re browsing for a study, you might also look at Trihexyphenidyl powder, Sunifiram powder, Tropisetron powder and Sulbutiamine powder. Our main Nootropics page lists everything in the category.
Buy TAK-653 powder from Umbrella Labs
Ordering takes a minute. Add it to your cart and check out. The TAK-653 powder is in stock and ready to ship. While you’re here, our lab supplies cover the pipettes, scales and solutions most studies need.
Sold for laboratory research use only. It isn’t for human or veterinary use, and it isn’t a food, drug or cosmetic.
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