Description
With this O-304 powder you get O-304 as loose powder. Each batch is tested by LC-MS to 99% purity or higher. It’s $49.99. It’s sold for laboratory research only.
The same compound comes in other formats too: O-304 capsules and O-304 liquid. See all research chemical powders for more options in this format.
What is O-304?
O-304 (ATX-304) is a pan-AMPK activator developed by Betagenon in Sweden. It works by stopping AMPK from being switched off.
It’s studied in diabetes and heart function.
O-304 powder specifications
- Compound: O-304 (ATX-304, OS-01)
- CAS number: 1261289-04-6
- Molecular formula: C16H11Cl2N3O2S
- Molecular weight: 380.2
- Purity: 99% or higher, tested by LC-MS
- Amount: 3g
- Form: Loose powder
- Storage: Keep it in a cool, dry place away from direct sunlight
- Use: laboratory research only, not for human or veterinary use
What studies say about O-304
Steneberg and colleagues reported in JCI Insight (2018) that O-304 lowered blood glucose and improved heart function in mice.
A small phase 2a trial in type 2 diabetes followed.
The original papers are on PubMed if you’d like to read them in full.
Weighing and handling O-304 powder
Buying O-304 as a powder gives you full control. Weigh out exactly what your protocol calls for, make up your own solutions, or encapsulate it yourself.
For small amounts you’ll want a scale that reads to at least 0.01g, and ideally 0.001g. Our digital scale and micro scoops make it easier to get consistent measurements. Weigh onto clean weighing paper, and close the bag or jar straight after so the powder doesn’t pick up moisture.
Making a solution from O-304 powder
To make a stock solution, decide on the final volume and concentration first. For 30mL at 10mg/mL you’d weigh 300mg of O-304, dissolve it in about 25mL of solvent, then top up to exactly 30mL.
Check the compound’s solubility in your chosen solvent before you start, and try a small test amount first. Store the finished solution in a labelled glass bottle.
How we test O-304
We test each batch of O-304 by LC-MS, which pairs liquid chromatography with mass spectrometry. The chromatography splits the sample into its components and the mass spectrometer identifies them, which tells you both identity and purity. This batch came in at 99% or higher.
Small differences between batches are normal, so write the batch number from the label into your records. If something looks wrong when your order arrives, like discoloured powder or a cloudy solution, set it aside and don’t use it.
Storing your O-304
Keep it in a cool, dry place away from direct sunlight. Use a clean, dry scoop each time, and reseal the container straight away. Label anything you decant with the compound, amount and date, and keep it out of reach of children and pets.
Common questions about the O-304 powder
What can I dissolve O-304 powder in?
That depends on the compound’s solubility and your protocol. Check the solubility data for your solvent first, and test a small amount before making up a full batch.
What scale do I need?
One that reads to 0.01g at minimum, and 0.001g for very small amounts. Our pocket scale reads to 0.01g.
Is the O-304 powder in stock?
Yes. Every option on this page is in stock and ready to ship.
Related research chemicals
If you’re browsing for a study, you might also look at Pyrilutamide powder, Nortadalafil powder, SANA powder and Mirogabalin powder. Our main Research Chemicals page lists everything in the category.
Buy O-304 powder online
Ready when you are. Add it to your cart and check out. The O-304 powder is in stock and ready to ship. While you’re here, our lab supplies cover the pipettes, scales and solutions most studies need.
Sold for laboratory research use only. It isn’t for human or veterinary use, and it isn’t a food, drug or cosmetic.
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