Description
With this SAM-e powder you get SAM-e as loose powder. Each batch is tested by LC-MS to 99% purity or higher. It’s $29.99. It’s sold for laboratory research only.
See all nootropic powders for more options in this format.
What is SAM-e?
SAM-e (S-adenosyl-L-methionine) is made from methionine and ATP and is the main methyl donor in cells. It’s sold here as the disulfate tosylate salt.
It’s a prescription drug in some European countries.
SAM-e powder specifications
- Compound: SAM-e (Ademetionine disulfate tosylate, Ademethionine Disulfate Tosylate, Zentonil)
- CAS number: 97540-22-2
- Molecular formula: C22H34N6O16S4
- Molecular weight: 766.8
- Purity: 99% or higher, tested by LC-MS
- Amount: 15g
- Form: Loose powder
- Storage: Keep it in a cool, dry place away from direct sunlight
- Use: laboratory research only, not for human or veterinary use
Research on SAM-e
Papakostas and colleagues reported in 2010 that SAM-e added to antidepressants helped some non-responders.
Reviews describe the evidence as mixed.
Search PubMed for the full studies. We stick to what’s been published.
Tips for measuring SAM-e powder
Buying SAM-e as a powder gives you full control. Weigh out exactly what your protocol calls for, make up your own solutions, or encapsulate it yourself.
For small amounts you’ll want a scale that reads to at least 0.01g, and ideally 0.001g. Our digital scale and micro scoops make it easier to get consistent measurements. Weigh onto clean weighing paper, and close the bag or jar straight after so the powder doesn’t pick up moisture.
Making a solution from SAM-e powder
To make a stock solution, decide on the final volume and concentration first. For 30mL at 10mg/mL you’d weigh 300mg of SAM-e, dissolve it in about 25mL of solvent, then top up to exactly 30mL.
Check the compound’s solubility in your chosen solvent before you start, and try a small test amount first. Store the finished solution in a labelled glass bottle.
Purity testing for SAM-e
Every batch of SAM-e is checked with liquid chromatography-mass spectrometry (LC-MS) before it goes on sale. LC-MS separates a sample into its parts and identifies each one by mass, so it confirms what the compound is and how much of the sample it makes up. The current batch tested at 99% or higher.
Small differences between batches are normal, so write the batch number from the label into your records. If something looks wrong when your order arrives, like discoloured powder or a cloudy solution, set it aside and don’t use it.
Storing your SAM-e
Keep it in a cool, dry place away from direct sunlight. Use a clean, dry scoop each time, and reseal the container straight away. Label anything you decant with the compound, amount and date, and keep it out of reach of children and pets.
Common questions about the SAM-e powder
What can I dissolve SAM-e powder in?
That depends on the compound’s solubility and your protocol. Check the solubility data for your solvent first, and test a small amount before making up a full batch.
What scale do I need?
One that reads to 0.01g at minimum, and 0.001g for very small amounts. Our pocket scale reads to 0.01g.
Is the SAM-e powder in stock?
Yes. Every option on this page is in stock and ready to ship.
Related nootropics
Similar products in this format include Sarcosine powder, S107 powder, Selenium powder and capsules and Roxadustat powder and capsules. Our main Nootropics page lists everything in the category.
Order the SAM-e powder from Umbrella Labs
Ready when you are. Add it to your cart and check out. The SAM-e powder is in stock and ready to ship. Need other compounds for the same study? Browse nootropic powders or our lab supplies.
Sold for laboratory research use only. It isn’t for human or veterinary use, and it isn’t a food, drug or cosmetic.
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